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KMID : 0359020080360010022
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Korean Journal of Gastrointestinal Endoscopy
2008 Volume.36 No. 1 p.22 ~ p.26
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A Granular Cell Tumor Located in the Gastric Cardia
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Park Jin-Sup
Kim Gwang-Ha
Kim Mi-Ra
Jeong Hong-Ryul
Cheong Jae-Hoon
Park Chan-Ho
Lee Sun-Mi
Kim Tae-Oh
Heo Jeong
Kang Dae-Hwan
Song Geun-Am
Cho Mong
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Abstract
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First described in 1926 by Abrikossoff, a granular cell tumor is a benign lesion and commonly involves the skin, connective tissue, and breast, but rarely the esophagus. The origin of granular cell tumors is controversial. The tumor is thought to arise from a Schwann cell origin, based on characteristics such as the positive expression of S-100 protein determined by immunohistochemical staining. A 29-year-old female was referred from the local clinic because of a polypoid lesion in the gastric cardia. After performing endoscopy and endoscopic ultrasonography, a 1.5 cm submucosal tumor covered with normal mucosa was found in the gastric cardia. Endoscopic mucosal resection revealed a tumor that initiated in the esophagus, and grew into the cardia. Immunohistochemical analysis revealed strong positive staining for S-100 protein, confirming the presence of a granular cell tumor. (Korean J Gastrointest Endosc 2008;36:22-26)
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KEYWORD
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Granular cell tumor, Gastric cardia, Endoscopic mucosal resection
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